i
Class IIb indications for digoxin therapy for reducing the risk of HF hospitalization:
CHF + NYHA Class II - IV symptoms + sinus rhythm + HR > 70 b.p.m.+ LVEF < 45% + poor tolerance of B-blockers,
CHF + NYHA Class II - IV symptoms persisting despite treatment with ACEI and MRA and B-blocker + LVEF < 45%,
CHF + NYHA Class II - IV symptoms persisting despite treatment with ARB and MRA and B-blocker + LVEF < 45%,
CHF + NYHA Class II - IV symptoms persisting despite treatment with ACEI and ARB and B-blocker + LVEF < 45%.
i